PhD, DSci, Professor, Member of the Russian Academy of Sciences

E-mail:

sergei.nedospasov@gmail.com

Affiliation:

Principal Scientist, Laboratory of Molecular Mechanisms of Immunity, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Head, Division of Immunobiology and Biomedicine, Sirius University of Science and Technology

Head, Immunology Department, Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University

Professor, Chair of Immunology, Biological Faculty, Lomonosov Moscow State University

Membership in professional societies:

Russian Society of Biochemistry and Molecular Biology

Russian Society of Immunologists

International Cytokine Society

American Association of Immunologists

German Society of Immunologists

Membership in editorial boards:

Cytology, Molecular Biology, Russian Journal of Immunology, Medical Immunology, European Journal of Immunology, Immunology Letters

Honors and other special professional recognition

• Russian Federation State Prize for Science and Technologies (Moscow, Russia, 2016)
• Elected Full Member of the Russian Academy of Sciences (Physico-Chemical Biology, 2016)
• Elected Member of the European Academy of Tumor Immunology (2012)
• I.I. Mechnikov Award from the Russian Academy of Sciences (2011)
• Elected Member of Academia Europaea (2010)
• Helmholtz-Humboldt Prize (Germany, 2005)
• Elected Associate Member of the Russian Academy of Sciences (Biotechnologies, 2003)
• Berlin-Brandenburg Academy Prize (Germany, 2000)
• Investigator Award (USA, 1991)

Teaching activities:

• Head, Chair of Immunology, Biological Faculty, Lomonosov Moscow State University (2009-2022)
• Lecturer in the special courses “Molecular Immunology”, “Mechanisms of Programmed Cell Death”, “Current Problems of Immunology” at Chair of Immunology, Faculty of Biology, Lomonosov Moscow State University
• Lecturer for high school students at the Sirius Educational Center, Foundation “Talent and Success”
• Head of the Master's Program “Immunology and Biomedicine” at Sirius University of Science and Technology
• Head of PhD Programs “Immunology” and “Cell Biology” at Sirius University of Science and Technology
• Supervision of diploma and PhD project works for undergraduate and postgraduate students at Lomonosov Moscow State University, Pirogov Russian National Research Medical University, Engelhardt Institute of Molecular Biology and Sirius University of Science and Technology

Selected publications:
>300 papers, >20000 citations, hi=60 (WoS), 74 (Google)

1. Tumanov A.V., Kuprash D.V., Lagarkova M.A., Abe K., Shakhov A.N., Drutskaya L.N., Stewart C.L., Chervonsky A.V., Nedospasov S.A. (2002) Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues. Immunity, 17: 239-250. doi: 10.1016/s1074-7613(02)00397-7.
2. Grivennikov S.I., Tumanov A.V., Liepinsh D.J., Kruglov A.A., Marakusha B.I., Shakhov A.N., Murakami T., Drutskaya L.N., Forster I., Clausen B.E., Tessarollo L., Ryffel B., Kuprash D.V., Nedospasov S.A. (2005) Distinct and non-redundant in vivo functions of TNF produced by T cells and macrophages/ neutrophils: protective and deleterious effects. Immunity, 22(1): 93-104. doi: 10.1016/j.immuni.2004.11.016.
3. Kruglov A.A., Grivenninkov S.I., Kuprash D.V., Winsauer C., Prepens S., Seleznik G.M., Eberl G., Littman D., Heikenwalder M., Tumanov A.V., Nedospasov S.A. (2013) Non-redundant function of soluble LTa3 produced by innate lymphoid cells in intestinal homeostasis. Science, 342(6163): 1243-1246. doi: 10.1126/science.1243364.
4. Efimov G.F., Kruglov A.A., Khlopchatnikova Z., Rozov F., Mokhonov V.V., Rose-John S., Scheller J., Gordon S., Stacey M., Drutskaya M.S., Tillib S.V., Nedospasov S.A. (2016) Cell type-restricted anti-cytokine therapy: TNF inhibition from one pathogenic source. Proc. Natl. Acad. Sci. USA, 113(11): 3006-3011. doi: 10.1073/pnas.1520175113.
5. Atretkhany K-S.N., Mufazalov I.A., Dunst J., Kuchmiy A.A., Gogoleva V.S., Andruszewski D., Drutskaya M.S., Faustman D.L., Schwabenland M., Prinz M., Kruglov A.A., Waisman A., Nedospasov S.A. (2018). Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity. Proc. Natl. Acad. Sci. USA, 115(51):13051-13056. doi: 10.1073/pnas.1807499115